Author

Mengying Zhou

Harvard UniversityORCID 0000-0002-7660-6805Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Organism:Xenopus· 1

Frequent Co-Authors

Ying LuiD· 2 shared Yuyu SongiD· 2 shared Alfred Lewis GoldbergiD· 1 shared Bert M. VerheijeniD· 1 shared Boyan LiiD· 1 shared Can Martin ZhangiD· 1 shared Christine M. FieldiD· 1 shared Dong Hoon LeeiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Ying LuORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedAug 22, 2025

Episodic Transport of Protein Aggregates Achieves a Positive Size Selectivity in Aggresome Formation

Rui Fang, Luolan Bai, Bert M. Verheijen…·Ying Lu

The paper investigates aggresome formation by reconstituting aggregate transport in Xenopus egg extract, finding that episodic dynein-mediated transport enables positive size selectivity.

4 citations

Xenopusproteomics

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Molecular BiologybioRxivPreprintMay 30, 2023

HUWE1 Amplifies Ubiquitin Modifications to Broadly Stimulate Clearance of Proteins and Aggregates

Mengying Zhou, Rui Fang, Louis Colson…·Ying Lu

This paper identifies HUWE1 as a ubiquitin ligase that enhances ubiquitin modifications on proteins and aggregates, promoting their degradation via proteasome and autophagy pathways.

16 citations

experimental assay

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