Author

Rui Fang

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alfred Lewis GoldbergiD· 1 shared Bing XuiD· 1 shared Binlin DaiD· 1 shared Can Martin ZhangiD· 1 shared Dong Hoon LeeiD· 1 shared Eric S. FischeriD· 1 shared Feng ZhangiD· 1 shared Gary Andrew BradshawiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Alfred Lewis GoldbergORCID

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2 papers

Recent·Most cited

SIRT4 enhances the cytotoxicity of NK cells toward hepatic stellate cells and reverses liver fibrosis via AMPKα/P-p53/NKG2DL pathway

Huan Chen, Binlin Da, Zihao Cai, Rui Fang, Xiaolin Xie, Han Zhang, Si Zhao, Ming Zhang, Lei Wang, Bing Xu, Yuzheng Zhuge, Feng Zhang

This study shows SIRT4 enhances NK cell cytotoxicity against HSCs and reverses liver fibrosis via the AMPKα/P-p53/NKG2DL pathway using AAV-mediated delivery.

bioRxiv · Sep 30, 2024 · PreprintCell Biology

HUWE1 Amplifies Ubiquitin Modifications to Broadly Stimulate Clearance of Proteins and Aggregates

Mengying Zhou, Rui Fang, Louis Colson, Katherine A. Donovan, Moritz Hunkeler, Yuyu Song, Can Martin Zhang, Si-Yi Chen, Dong Hoon Lee, Gary Andrew Bradshaw, Robyn J. Eisert, Yihong Ye, Marian Kalocsay, Alfred Lewis Goldberg, Eric S. Fischer, Ying Lu

This paper identifies HUWE1 as a ubiquitin ligase that enhances ubiquitin modifications on proteins and aggregates, promoting their degradation via proteasome and autophagy pathways.

bioRxiv · May 30, 2023 · PreprintMolecular Biology