Author

Tracy J. Ballinger

Institute of Genetics and CancerORCID 0000-0002-7689-0009Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alison M. MeynertiD· 2 shared Colin A M SempleiD· 2 shared Ailith EwingiD· 1 shared Alhafidz HamdaniD· 1 shared Andrew J. WoodiD· 1 shared Andrew Victor BiankiniD· 1 shared Athena MatakidouiD· 1 shared Brian Andrew DoughertyiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Alison M. MeynertORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJul 1, 2025

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

Ailith Ewing, Alison M. Meynert, Ryan Silk…·Colin A M Semple

The paper identifies two divergent structural variation trajectories in HGSOC that impact patient survival and reveals novel candidate driver genes and mtDNA mutations associated with prognosis.

19 citationstop 3%

humanwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsGenome biologyPeer-reviewedFeb 8, 2019

Modelling double strand break susceptibility to interrogate structural variation in cancer

Tracy J. Ballinger, Britta A. M. Bouwman, Reza Mirzazadeh…·Colin A M Semple

The paper develops genome-wide models of DNA double strand break (DSB) susceptibility to identify structural variants (SVs) under positive or purifying selection in cancer.

25 citations

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsPLoS BiologyPeer-reviewedDec 12, 2018

Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence repair outcome

Kallimasioti Pazi, Keerthi T. Chathoth, Gillian C.A. Taylor…·Andrew J. Wood

The paper shows heterochromatin slows CRISPR-Cas9 mutagenesis but does not affect repair outcomes, with mutagenesis inhibition depending on Cas9 exposure levels.

98 citations

mouseCRISPR screen

𝕏 PostBluesky