Human memory CD4+ T cells recognize non-infected macrophage bystanders exposed to Mycobacterium tuberculosis-infected cells
Vinicius G. Suzart, Robert Schauner, Scott M. Reba, Daniel P. Gail, Gwendolyn M. Swarbrick, David Michael Lewinsohn, Deborah A. Lewinsohn, Bianca A. Lepe, Bryan D. Bryson, Samuel M. Behar, Christopher M. Sassetti, Michael L. Freeman, W Henry Boom, Clifford V. Harding, Stephen M. Carpenter
The paper shows human memory CD4+ T cells recognize both Mtb-infected and bystander macrophages, with some TCRs specifically recognizing infected cells.
bioRxiv · Sep 24, 2026 · PreprintImmunology