Author

Penghui Lin

University of KentuckyORCID 0000-0002-7733-7782Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Chaohao LiiD· 1 shared Chi WangiD· 1 shared Daheng HeiD· 1 shared Derek B. AllisoniD· 1 shared Donald A. MorganiD· 1 shared Eunus Sheemul AliiD· 1 shared Heba Qaissi· 1 shared Hunter MoseleyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Chaohao LiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PLK1-mediated phosphorylation of PHGDH reprograms serine metabolism in advanced prostate cancer

Xiongjian Rao, Derek B. Allison, Robert M Flight, Penghui Lin, Daheng He, Zhiguo Li, Yanquan Zhang, Ruixin Wang, Chaohao Li, Jianlin Wang, Xinyi Wang, Jia Peng, Ka-wing Fong, Qing Shao, Chi Wang, , Xiaoqi Liu

The paper identifies PLK1-mediated phosphorylation of PHGDH as a mechanism driving serine metabolism reprogramming in advanced prostate cancer, increasing reliance on exogenous serine uptake.

Proceedings of the National Academy of Sciences · Jul 27, 2026Peer-reviewedCancer Biology

Metabolic Reprogramming Coordinates Mannose and Glutamine Metabolism to Maintain Glucose Homeostasis During Glycosuria

Nadia Rashid, Moses Temitayo Otunla, Nazmul Hasan, Michael J. Hodges, Heba Qaissi, Tumininu S. Faniyan, Pontiana Ritika Clement, Penghui Lin, Mohamed M. Y. Kaddah, Teresa Cassel, Donald A. Morgan, Kamal Rahmouni, Kavaljit H. Chhabra

The paper identifies coordinated metabolic adaptations in mannose and glutamine pathways during glycosuria to maintain glucose homeostasis, showing their dependence on SGLT2 inhibitor treatment.

bioRxiv · May 22, 2026 · PreprintPhysiology