Author

Yamel Cardona Gloria

University of TübingenORCID 0000-0002-9118-8779Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander N.R. WeberiD· 2 shared Sabine DickhöferiD· 2 shared Alfred G. ZimmerliniD· 1 shared Andrea A. GustiD· 1 shared Andreas HofmanniD· 1 shared Anurag Singh· 1 shared Artiom CernijenkoiD· 1 shared Ashley A. Burke· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Alexander N.R. WeberORCID

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2 papers

Recent·Most cited

A cereblon (CRBN) molecular glue degrader of NIMA-related kinase 7 (NEK7) reveals a context-dependent role in NLRP3 inflammasome activation

Aude Sylvain, Natacha Stoehr, Fupeng Ma, Artiom Cernijenko, Martin Schröder, Maryam Khoshouei, Melanie Vogelsanger, Michel Schoenboerner, Ashley A. Burke, Pasupuleti Rao, Jonathan M. Solomon, Joshiawa Paulk, Lei Xu, Janet Dawson, Damien Begue, , Zuni I. Bassi

This paper identifies NK7-902, a CRBN molecular glue degrader of NEK7, showing partial inhibition of NLRP3 inflammasome activation in humans and full activity in mice, but only transient effects in non-human primates.

Cell chemical biology · Jul 1, 2025Peer-reviewedImmunology

The fungal ligand chitin directly binds and signals inflammation dependent on oligomer size and TLR2

Katharina Fuchs, Yamel Cardona Gloria, Olaf-Oliver Wolz, Franziska Herster, Lokesh Sharma, Carly Dillen, Christoph Täumer, Sabine Dickhöfer, Zsofia Bittner, Truong-Minh Dang, Anurag Singh, Daniel Haischer, Maria A. Schlöffel, Kirsten J. Koymans, Tharmila Sanmuganantham, , Alexander N.R. Weber

This study identifies chitin oligomers as the smallest immunologically active motif and TLR2 as the primary receptor for chitin, showing size-dependent signaling and therapeutic potential.

bioRxiv · Mar 5, 2018 · PreprintImmunology