Author

Eric M. Ndombi

Kenyatta UniversityORCID 0000-0002-7809-4452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Frédéric D. ChevalieriD· 3 shared Timothy J. C. AndersoniD· 3 shared Winka Le ClecʼhiD· 3 shared John K. Oguso· 2 shared Madison MoralesiD· 2 shared Peter Olilah· 2 shared Aidan Mark EmeryiD· 1 shared Amaya L. BustinduyiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Frédéric D. ChevalierORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pooled amplicon sequencing for characterizing mutations in the praziquantel molecular target TRPMPZQ in schistosome populations from Western Kenya

Peter Olilah, Frédéric D. Chevalier, John K. Oguso, Erick Oyugi, Benjamin Opot, Madison Morales, Winka Le Clecʼh, Timothy J. C. Anderson, Eric M. Ndombi

This study analyzes mutations in the Praziquantel target gene Sm.TRPMPZQ in schistosome populations from Western Kenya to assess their role in drug resistance.

bioRxiv · Aug 9, 2026 · PreprintGenomics

Direct measurement of in vitro response to Praziquantel in Schistosoma mansoni populations from Western Kenya

Eric M. Ndombi, John K. Oguso, Peter Olilah, Churchill Orao, Brian Otieno Onyando, Madison Morales, Winka Le Clecʼh, Frédéric D. Chevalier, Timothy J. C. Anderson

The paper directly assays PZQ response in S. mansoni worms from Western Kenya and finds no evidence of PZQ resistance.

bioRxiv · Jul 22, 2026 · PreprintMicrobiology

TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants

Claudia M. Rohr, Sang-Kyu Park, Kelsilandia Aguiar-Martins, Timothy J.C. Anderson, Duncan Berger, Matthew Berriman, Sarah K. Buddenborg, Amaya L. Bustinduy, Frédéric D. Chevalier, James Anthony Cotton, Thomas Crellen, Stephen R. Doyle, Aidan Mark Emery, Julien Kincaid-Smith, Safari Kinung'hi, , Jonathan S. Marchant

TRPtracker aggregates TRPMPZQ variants and their PZQ sensitivity data to monitor resistance and support schistosomiasis control strategies.

International Journal for Parasitology Drugs and Drug Resistance · Mar 18, 2026Peer-reviewedMicrobiology