Satchidananda Panda

The paper develops a multi-vector RNA End Joining system for Duchenne muscular dystrophy that enables efficient expression of large therapeutic proteins with minimal off-target effects.

This study investigates circadian disruption in Alzheimer's disease using APP/PS1 mice, finding gene expression and connectomic changes in the SCN independent of amyloid beta deposits.

This study uses EEG/EMG recordings and machine learning to analyze how time-restricted feeding affects sleep microarchitecture in mice on a high-fat diet, finding it reduces sleep fragmentation and enhances specific NREM substates.

The paper shows that ketone bodies support thermogenic adaptation in BAT during fasting by promoting lipid remodeling and thermogenesis.

The paper profiles the active cistrome in peripheral leukocytes of critically ill COVID-19 patients to identify severity-associated cis-regulatory elements and their regulatory programs.

The paper maps synaptic connectivity patterns in the SCN core and shell using EM techniques, showing the shell receives denser mRGC inputs than the core.

This study identifies miR-183/96/182 as a circadian modulator through a genome-wide miRNA screen and validates its function in vitro and in vivo.

This study shows that activating astroglia in the lateral habenula prevents the antidepressant effect of bright light stimulation in a mouse model resistant to antidepressants.

This study revives light-evoked neuronal signals in postmortem mouse and human retinas, showing that cone photoreceptor responses can be restored up to 5 hours postmortem, with hypoxia being the main cause of irreversible signal loss.