Junjie Zhang

A reference genome without a virus: cDNA reconstruction reveals the provenance and function of the MS2 phage sequence

The paper reconstructs the MS2 phage genome using cDNA and shows that the current NCBI reference genome does not produce infectious phage, highlighting the need to verify reference genome infectivity.

Genome-wide characterization of host factors involved in single-stranded RNA and DNA phage infection pathways

This study identifies host factors critical for ssRNA and ssDNA phage infection in E. coli, revealing conserved dependencies and lineage-specific requirements.

Predicting Capsid Protein Binding Sites in Single-Stranded RNA Viruses Using Machine Learning from Local Geometric Features

This paper develops a machine learning framework to predict capsid protein binding sites in ssRNA viruses using local geometric features from RNA structures, achieving high accuracy with and without experimental data.

Suppressing Transfer of Antibiotic Resistance by a Small RNA Virus

This paper shows that the ssRNA phage PRR1 inhibits conjugation of the IncP plasmid RP4 by targeting its T4SS pilus, with non-infectious PRR1 particles sufficient for inhibition.

GTP hydrolysis triggers membrane remodeling by AMPH-1

This study shows that GTP hydrolysis by AMPH-1 drives membrane remodeling through oligomerization and tubulation, essential for transport carrier formation.