Tatsuya Sawasaki

Androgen receptor determines skeletal muscle sexual dimorphism

This study identifies AR-dependent Mybph repression as a mechanism contributing to skeletal muscle sexual dimorphism using ChIL-seq and an AirID-AR knock-in mouse.

Comparative Proteomic Profiling of Receptor Kinase Signaling Reveals Key Trafficking Components Enforcing Plant Stomatal Development

The paper identifies key trafficking components involved in ERECTA receptor kinase signaling that regulate plant stomatal development through endocytosis.

LRBA promotes drug-induced liver injury and MASLD by scaffolding MAPK activation

This study identifies LRBA as a scaffold promoting MAPK activation, leading to drug-induced liver injury and MASLD by enhancing inflammatory signaling.

Sex-biased transcriptome in embryonic mouse cortices under Pax6 haploinsufficiency highlights Pbdc1 as a candidate regulator

The paper identifies sex-biased transcriptome changes in Pax6 haploinsufficient mouse cortices and highlights Pbdc1 as a candidate regulator of sex-dependent corticogenesis.

In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID

The paper validates target proteins of heterobifunctional molecules using AirID, showing different interactome profiles based on E3 ligase binders.