Erin H. Seeley

The paper maps age-related changes in the N-glycoproteome across multiple tissues in mice, showing how glycosylation affects autoantibody binding to MOG in the brain.

This study shows that loss of Leiomodin1 in vascular smooth muscle cells causes rapid coronary atherosclerosis in mice, independent of actin nucleation, and highlights Thbs1 as a target for mitigating foam cell formation.

This study characterizes the spatiotemporal metabolic changes in the brain after traumatic injury, identifying distinct metabolic responses in microglia/macrophages and astrocytes.

This study develops SABER hydrogels that extend drug release and therapeutic effect for small molecules and biologics in preclinical models.

This paper develops a machine learning-guided hydrogen-bonded organic framework for ultrasound-triggered pain therapy, showing effective long-term analgesia in a rat model.

This study uses spatial omics to identify distinct tumor microenvironment profiles in Black and White American TNBC patients, linking them to different immunosuppressive mechanisms and clinical outcomes.

This study shows that loss of LATS1/2 in endothelial cells promotes a senescence-associated stemness (SAS) state, leading to atherothrombotic plaque formation through metabolic and mitochondrial dysregulation.

The paper integrates spatial multi-omics data from diffuse gliomas to identify locoregional metabolomic regulators linked to glioma growth and treatment resistance.

This study shows that a ketomimetic medium increases chemoresistance and invasiveness of breast cancer cells through hypersialylation and lipid synthesis pathways.