Author

Karine Cambon

Centre National de la Recherche ScientifiqueORCID 0000-0001-9263-4366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Anne‐Sophie HérardiD· 2 shared Fanny PetitiD· 2 shared Alexis‐Pierre BemelmansiD· 1 shared Carole EscartiniD· 1 shared Charlène JoséphineiD· 1 shared Charles J. DuyckaertsiD· 1 shared Emmanuel BrouilletiD· 1 shared Gilles BonventoiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Anne‐Sophie HérardORCID

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2 papers

Recent·Most cited

Pathological changes induced by Alzheimer's brain inoculation in amyloid-beta plaque bearing mice

Suzanne Lam, Anne‐Sophie Hérard, Susana Boluda, Fanny Petit, Sabiha Eddarkaoui, Karine Cambon, The Brainbank Neuro-CEB Neuropathology Network, Jean‐Luc Picq, Luc Buée, Charles J. Duyckaerts, Stéphane Haı̈k, Marc Dhénain

This study shows that injecting human Alzheimer's brain extracts into mice with amyloid-beta plaques induces tau pathology, memory deficits, and synaptic loss, with neuritic plaques linked to synaptic impairment.

bioRxiv · Apr 6, 2021 · PreprintNeuroscience

Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease

Océane Guillemaud, Kelly Ceyzériat, Thomas Saint-Georges, Karine Cambon, Fanny Petit, Lucile Ben Haim, María-Angeles Carrillo-de Sauvage, Martine Guillermier, Suéva Bernier, Anne‐Sophie Hérard, Charlène Joséphine, Alexis‐Pierre Bemelmans, Emmanuel Brouillet, Philippe Hantraye, Gilles Bonvento, Carole Escartin

This study investigates the role of reactive astrocytes in Alzheimer's disease by modulating the JAK2-STAT3 pathway in 3xTg-AD mice, finding no effect on Tau or amyloid pathology but behavioral changes.

bioRxiv · Oct 8, 2019Neuroscience