Author

Jesús M. Santiago-Borges

Washington University in St. LouisORCID 0000-0002-4710-3993Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron J. SchmitziD· 1 shared Ali H. EllebedyiD· 1 shared Andrew L. KauiD· 1 shared Brian M. EganiD· 1 shared Daniel L. SchneideriD· 1 shared Denise A. SanickiD· 1 shared Edward D. B. LopattoiD· 1 shared Elena D. BagatelasiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Aaron J. SchmitzORCID

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2 papers

Recent·Most cited

MicrobiologyScience AdvancesPeer-reviewedJun 20, 2025

Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI

Edward D. B. Lopatto, Jesús M. Santiago-Borges, Denise A. Sanick…·Scott J. Hultgren

This study identifies two monoclonal antibodies against FimH adhesin that protect mice from E. coli UTI by sterically blocking FimH function, offering an antibiotic-sparing treatment strategy.

22 citationstop 1%

mouseexperimental assay

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GeneticsbioRxivPreprintMar 4, 2022

Notch signaling in germ line stem cells controls reproductive aging in C. elegans

Zuzana Kocsisova, Elena D. Bagatelas, Jesús M. Santiago-Borges…·Kerry Kornfeld

This study identifies Notch signaling in the distal germline as a root cause of reproductive aging in C. elegans by showing that ectopic expression of the Notch effector gene SYGL-1 delays aging.

4 citations

C. elegansexperimental assay

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