Jackson S. Turner

mRNA-based influenza vaccine expands breadth of B cell response in humans

An mRNA-based influenza vaccine induces broader and more durable B cell responses compared to inactivated influenza virus vaccine in humans.

Defining a highly conserved B cell epitope in the receptor binding motif of SARS-CoV-2 spike glycoprotein

Booster SARS-CoV-2 mRNA vaccine recruits and broadens GC B cell responses targeting a highly conserved site on receptor binding domain of spike glycoprotein.

Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI

This study identifies two monoclonal antibodies against FimH adhesin that protect mice from E. coli UTI by sterically blocking FimH function, offering an antibiotic-sparing treatment strategy.

Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin

This study identifies key structural and glycosylation features of EtpA, an ETEC adhesin, and shows how antibodies target different epitopes to influence immune responses and pathogen-host interactions.

B cell receptor crosslinking can augment T cell help-mediated germinal center B cell selection.

This study shows that T cell help alone can drive GC B cell expansion and plasmablast formation, while BCR crosslinking synergizes with T cell help to enhance these responses when T cell help is limited.

B cells transiently exposed to antigen that return to quiescence respond to protein immunization similarly to naive B cells

The paper shows that B cells previously exposed to antigen and then inactivated respond similarly to immunization as naive B cells.