Author

Sofian Al Shboul

Hashemite UniversityORCID 0000-0002-0455-4380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Javier A. AlfaroiD· 2 shared Ted R. HuppiD· 2 shared A. R. S. BlackiD· 1 shared Ajitha RajaniD· 1 shared Alan SerrelsiD· 1 shared Alexander E.P. LoftusiD· 1 shared Bořivoj VojtěšekiD· 1 shared Colin SmithiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Javier A. AlfaroORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

FAK inhibitor treatment systemically regulates the glioblastoma immune environment via blocking monocyte trafficking

Emily R. Webb, A. R. S. Black, Giovana Carrasco, Muhammad Furqan, Robert L. Hollis, Alexander E.P. Loftus, Joel A Ochoa, Romain Enjalbert, Tara Best, Xiaozhong Peng, Morwenna Muir, Fraser Laing, Martin W. Lee, Sofian Al Shboul, Tongjie Wang, , Valerie G. Brunton

This study shows that systemic FAK inhibition reduces immunosuppressive macrophages in glioblastoma by blocking monocyte trafficking, enhancing T cell activity and improving survival in a mouse model.

bioRxiv · Nov 26, 2025 · PreprintImmunology

Multi-omics integration in Esophageal Adenocarcinoma reveals therapeutic targets and EAC-specific regulation of protein abundances

J. Robert O’Neill, Marcos Yébenes Mayordomo, Goran Mitulović, Sofian Al Shboul, Georges Bedran, Jakub Faktor, Lenka Hernychová, Lukáš Uhrík, Maria Gómez-Herranz, Mikołaj Kocikowski, Vicki Save, Bořivoj Vojtěšek, Mark Johan Arends, Ted R. Hupp, Javier A. Alfaro

The paper identifies GPA33 as an EAC-specific biomarker and reveals post-transcriptional regulation of protein expression in EAC through multi-omics integration.

medRxiv · Nov 24, 2022 · PreprintGenetic & Genomic Medicine