MicrobiologybioRxivPreprint
NINJ1 mediates necrosis of Mycobacterium tuberculosis infected human macrophages
Ragnhild SR Sætra, Mathilde Hansen, Shirin Kappelhoff…·Trude Helen Flo
This study identifies NINJ1 as a mediator of plasma membrane rupture in Mtb-infected macrophages, showing it operates independently of canonical cell death pathways and requires the ESX-1 secretion system.
3 citations