John H. Morrison

This study links neuronal population organization disruption to behavioral changes in a macaque model of early-stage Alzheimer's disease and related dementias.

The paper shows that reduced independence in neuronal representations predicts cognitive decline in Alzheimer's disease models and humans.

The paper identifies two types of beta bursts in primate motor cortex during motor tasks and shows their distinct roles in movement control and recovery after stroke.

This study compares extrasynaptic and synaptic NMDAR-GluN2B expression in macaque subgenual cingulate and dorsolateral prefrontal cortices using immunoelectron microscopy, finding higher extrasynaptic expression in subgenual cortex and higher synaptic expression in dorsolateral prefrontal cortex.

This study creates normative brain growth charts for rhesus macaques across their lifespan using MRI data, revealing developmental milestones and cross-species comparisons with humans.

The paper identifies CCR7+ CD4 T cells in rhesus brain and border tissues, showing their decline during chronic SIV-induced neuroinflammation and their role in CNS immune surveillance.

This study investigates CD4 T cell responses in the CNS during SIV infection in rhesus macaques, revealing their role in viral persistence and immune activation despite ART.

This paper demonstrates head-mounted microendoscopic calcium imaging in rhesus macaques, enabling long-term, high-resolution recording of neural activity during natural motor tasks.

Macaque fetuses infected with Zika virus show both macro- and micro-scale neuropathological abnormalities, including decreased gyrencephality, relative increases in cortical white matter, activation of glia, and increased apoptosis.

This study shows SARS-CoV-2 infection in rhesus macaques induces Tfh cells and germinal center responses, with Th1 skewing and early IgG but delayed IgA.

This study shows that starting estradiol treatment more than 2 years after menopause in aged rhesus monkeys improves cognitive function, while stopping treatment later does not reduce cognitive benefits.

This study investigates the effects of Aβ oligomers on synaptic pathology and neuroinflammation in a female rhesus monkey model of Alzheimer’s disease, finding significant synaptic loss and inflammatory responses.

The paper introduces PRIME-DE, an open resource for non-human primate MRI data, aggregating 13 datasets from 11 sites across 98 macaques.