Eliza Bliss‐Moreau

Loss of calbindin and rise in pT217-tau in aging monkey prefrontal cortical dendrites

The paper shows that aging macaques lose calbindin and gain pT217-tau in prefrontal cortical dendrites, linking calbindin loss to increased tau pathology and AD risk.

Cellular basis for cortical network aging in primates

The paper integrates spatial transcriptomics and cortical networks in macaques to identify cellular correlates of aging, finding age-related declines in transmodal networks linked to inhibitory and glial cells.

A pragmatic reevaluation of the efficacy of nonhuman primate optogenetics for psychiatry

The paper reevaluates the efficacy of nonhuman primate optogenetics for psychiatry, finding lower success rates when applying more relevant criteria to human neuropsychiatric disease.

Neuroanatomical abnormalities in a nonhuman primate model of congenital Zika virus infection

Macaque fetuses infected with Zika virus show both macro- and micro-scale neuropathological abnormalities, including decreased gyrencephality, relative increases in cortical white matter, activation of glia, and increased apoptosis.

Timing of Cyclic Estradiol Treatment Differentially Affects Cognition in Aged Female Rhesus Monkeys

This study shows that starting estradiol treatment more than 2 years after menopause in aged rhesus monkeys improves cognitive function, while stopping treatment later does not reduce cognitive benefits.

Quantitative analysis of synaptic pathology and neuroinflammation: an initial study in a female rhesus monkey model of the “synaptic” phase of Alzheimer’s disease

This study investigates the effects of Aβ oligomers on synaptic pathology and neuroinflammation in a female rhesus monkey model of Alzheimer’s disease, finding significant synaptic loss and inflammatory responses.