Author

Lynn Scherpe

ETH ZurichORCID 0000-0002-8330-4653Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Benjamin G. HaleiD· 1 shared Boris Korablev· 1 shared Eric J. AirdiD· 1 shared Hao LiuiD· 1 shared Jacob E. CorniD· 1 shared Jess Gerrit SnedekeriD· 1 shared Julius RabliD· 1 shared Kevin GroeniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Benjamin G. HaleORCID

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2 papers

Recent·Most cited

ImmunologyNature Cell BiologyPeer-reviewedMar 13, 2026

SP110 sequestration of SP100 protects against toxic filaments during innate immune signaling

Eric J. Aird, Julius Rabl, Tabea Knuesel…·Jacob E. Corn

The paper identifies SP110 as a negative regulator of type 1 interferon-driven cell death by counteracting SP100's toxic filament formation through CARD domain interactions.

5 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky

BioengineeringBiofabricationPeer-reviewedApr 17, 2025

Filamented Light (FLight) Biofabrication of Mini-Tendon Models Show Tunable Matrix Confinement and Nuclear Morphology

Hao Liu, Lynn Scherpe, Linnea B. Hummer…·Marcy Zenobi‐Wong

This paper develops a biofabrication method to create mini-tendons with tunable matrix stiffness and microchannel dimensions, showing that mechanical confinement influences nuclear morphology and cell alignment.

13 citationstop 2%

organoid / primary cultureexperimental assay

𝕏 PostBluesky