Timothy E. Audas

Regulation of NFKBIZ by precise Regnase-1 endoribonuclease cleavage and subsequent uridylation

The paper shows Regnase-1 cleaves and uridylates NFKBIZ mRNA, enhancing its decay and linking this process to lymphoma and viral pathogenesis.

PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc

The paper identifies PI3K/AKT signaling as a mediator of stress-induced amyloid aggregation through c-myc activation and repression of GSK3 degradation.

A CREBZF/Zhangfei isoform activates CHOP during prolonged cellular stress

The paper identifies a CREBZF isoform, stZF, that activates CHOP during prolonged ER stress, promoting apoptosis and suggesting CREBZF's role in the Integrated Stress Response.

Coding and regulatory drivers of mantle cell lymphoma identified through exome and genome sequencing

This study identifies genetic drivers of mantle cell lymphoma through exome and genome sequencing, revealing novel mutations in genes involved in RNA splicing and regulation.

Genome-wide discovery of somatic coding and regulatory variants in Diffuse Large B-cell Lymphoma

This study identifies somatic coding and regulatory variants in DLBCL, revealing novel mechanisms of oncogene deregulation and potential therapeutic targets.