Author

Daniel A. Mordes

University of California, San FranciscoORCID 0000-0002-8344-2140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Abby Oehler· 1 shared Alexander I. P. TayloriD· 1 shared Annemarie F. CharvatiD· 1 shared Anthony YungiD· 1 shared Arthur Alves de MeloiD· 1 shared Carlo CondelloiD· 1 shared Daniel R. SouthworthiD· 1 shared Emma C. CarrolliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Abby Oehler

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2 papers

Recent·Most cited

Methods for high throughput discovery of fluoroprobes that recognize tau fibril polymorphs

Emma C. Carroll, Hyunjun Yang, Wyatt C. Powell, Annemarie F. Charvat, Abby Oehler, Julia G. Jones, Kelly M. Montgomery, Anthony Yung, Zoe Millbern, Alexander I. P. Taylor, Martin Wilkinson, Neil A. Ranson, Sheena E. Radford, Nelson R. Vinueza, William F. DeGrado, , Jason E. Gestwicki

The paper develops a high-throughput method to identify fluoroprobes that distinguish between tau fibril polymorphs using paDSF and chemical screening.

Nature Chemistry · Aug 14, 2025Peer-reviewedBiochemistry

Structure of a novel α-synuclein filament fold from multiple system atrophy

N. L. Yan, Francisco Candido, Eric Tse, Arthur Alves de Melo, Stanley B. Prusiner, Daniel A. Mordes, Daniel R. Southworth, Nick A. Paras, Gregory E. Merz

The paper determines the structure of a novel α-synuclein filament fold in multiple system atrophy using cryo-EM, identifying a new filament type distinct from other synucleinopathies.

FEBS Letters · Nov 7, 2024Peer-reviewedBiophysics