Author

Anne‐Karina T. Perl

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-8445-4565Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Jenna Green· 2 shared Minzhe GuoiD· 2 shared Adnan Cihan Cakar· 1 shared Alexander Gerhard MiethkeiD· 1 shared Andrew Wagner· 1 shared Ashley R. BurgiD· 1 shared Cheng JiangiD· 1 shared Cheng-Lun NaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenomics

Jenna Green

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Decoding Lymphangioleiomyomatosis (LAM) Niche Environment via Integrative Analysis of Single Cell Multiomics and Spatial Transcriptomics

Ken Chen, Shuyang Zhao, Minzhe Guo, Hasan Reza, Andrew Wagner, Adnan Cihan Cakar, Cheng Jiang, Erik Y. Zhang, Jenna Green, Emily P. Martin, Grace A. Wikenheiser, Kathryn A. Wikenheiser‐Brokamp, Anne‐Karina T. Perl, Debora I. Sinner, Jane J. Yu, Yan Xu

This study identifies two distinct LAM subtypes and their microenvironmental interactions using multi-omics and spatial transcriptomics, revealing key regulatory networks and potential therapeutic targets.

European Respiratory Journal · Jun 25, 2026Peer-reviewedGenomics

Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts

Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle A. Sargent, Mike Adam, Qing Ma, Anne‐Karina T. Perl, Alexander Gerhard Miethke, Ashley R. Burg, Tiffany Shi, David A. Hildeman, E. Steve Woodle, Matthew J. Kofron, Prasad Devarajan

The paper identifies Gucy1α1 as a specific marker for fibroblasts in multiple organs, showing its expression increases in fibrotic conditions across mouse and human tissues.

Scientific Reports · Nov 26, 2024Peer-reviewedMolecular Biology

Matrix fibroblast function during alveolarization is dependent on GATA6

Mereena George Ushakumary, Jenna Green, Matthew Riccetti, Cheng-Lun Na, Divya Mohanraj, Minzhe Guo, Anne‐Karina T. Perl

This study shows that GATA6 is essential for matrix fibroblast function during alveolarization, as its loss impairs alveolarization and disrupts AT1 cell differentiation.

bioRxiv · Jun 6, 2022 · PreprintDevelopmental Biology