Author
University of Massachusetts Chan Medical SchoolORCID 0000-0002-8509-1268Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Paula E. Grasberger, Abigail Sondrini, Nicole C. Glidden…·Kiera Clayton
The paper shows HIV uses Vpr to increase TRAIL-R2 expression in CD4+ T cells, which enhances NK cell killing through non-canonical TRAIL signaling.
Andrea Gramatica, Itzayana G. Miller, Adam R. Ward…·R. Brad Jones
The paper shows that tazemetostat reduces HIV reservoirs and improves CD8+ T-cell function by increasing MHC-I expression and promoting anti-HIV immune responses.
Karl Frontzek, Marco Bardelli, Assunta Senatore…·Adriano Aguzzi
This study identifies an H-latch conformational switch in PrPC that drives prion toxicity and shows that disrupting this switch can protect against prion-related neurodegeneration.