Kiera Clayton

This study identifies MARCO as a decoy LPS sensor regulated by non-canonical TLR signaling, which restricts inflammasome activation and prevents excessive inflammation.

The paper shows HIV uses Vpr to increase TRAIL-R2 expression in CD4+ T cells, which enhances NK cell killing through non-canonical TRAIL signaling.

This study shows HIV Nef induces a soft phenotype in infected CD4+ T cells, reducing their susceptibility to cytotoxic T lymphocyte killing through cytoskeletal remodeling and intrinsic heterogeneity.

The paper shows that tazemetostat reduces HIV reservoirs and improves CD8+ T-cell function by increasing MHC-I expression and promoting anti-HIV immune responses.