Olle Korsgren

Spatial and functional mapping of the human pancreas reveals endocrine and exocrine cell states in health and metabolic disease

This study maps spatial and functional states of human pancreatic cells in health and disease using combined single-cell and spatial transcriptomics with calcium imaging.

Single-cell proteomics of pancreatic islet cells reveals type 1 diabetes and donor-specific features

The paper performs single-cell proteomics on pancreatic islets from healthy and T1DM donors, identifying cell type-specific differences and donor-specific features.

Deep tissue optical 3D imaging reveals preferential preservation of extra-islet β-cells in late-onset Type 1 Diabetes

This study uses 3D optical imaging to show that extra-islet β-cells are more preserved in late-onset Type 1 Diabetes compared to islet-associated β-cells.

Islet Gene View - a tool to facilitate islet research

The paper introduces Islet Gene View (IGW), a platform that integrates gene expression and phenotypic data from pancreatic islets to explore T2D-related gene expression changes and their functional implications.