Marika Sjöqvist

Receptor stoichiometry predicts artery-typical vulnerability to altered Notch signaling during smooth muscle differentiation.

This study shows Notch2 drives canonical Notch signaling in smooth muscle differentiation, while Notch3 requires higher doses to activate transcription due to weaker RBPJκ interaction, with implications for artery-specific diseases.

Sex differences and risk factors for bleeding in Alagille syndrome

The paper identifies sex differences in bleeding risk and explores non-invasive vascular analysis in Alagille syndrome using mouse models and retinography.