Myosin VI orchestrates estrogen-driven gene expression in breast cancer cells.
Yukti Hari‐Gupta, Danielle Lambert, Isabel W. Shahid-Fuente, Natalia Fili, Ália dos Santos, Alexandria R. Sprules, Hyejeong Rosemary Kim, Alexander W. Cook, Peter J. I. Ellis, Jesse Aaron, Teng‐Leong Chew, Lin Wang, Christopher P. Toseland
This study shows Myosin VI regulates estrogen receptor activity and gene expression in breast cancer, with MVI inhibition enhancing hormone therapy effectiveness.
bioRxiv · Nov 13, 2025 · PreprintCancer Biology