Yoland Smith

This study uses 3D electron microscopy to compare synaptic connectivity and mitochondrial morphology in thalamic nuclei of control and Parkinsonian Rhesus Monkeys, finding increased corticothalamic terminal volume and altered mitochondrial complexity in CM neurons.

HiCAT improves spatial omics annotation by combining unsupervised clustering with atlas guidance, revealing molecularly defined regions and enhancing downstream analysis.

This study investigates the effects of GluD1 deletion on synapse ultrastructure in mice, finding no significant changes in synaptic morphology despite functional deficits.

The paper simulates Parkinson's disease effects on primary motor cortex neurons, showing increased beta band power in simulated networks.

This study maps RGS14 protein expression in the adult mouse brain, revealing broader expression than previously known in regions involved in cognitive functions and behavior.

This study uses 3D electron microscopy to show structural changes in GABAergic pallidothalamic terminals in MPTP-treated monkeys, revealing increased terminal volume, synapse surface area, and mitochondrial volume in specific thalamic nuclei.

This study shows that tyrosinase-induced neuromelanin accumulation in mouse locus coeruleus neurons causes hyperactivity, transcriptional changes, and degeneration, mimicking early stages of Alzheimer's and Parkinson's disease.

This study shows RGS14 protects hippocampal neurons from seizure-induced mitochondrial oxidative stress and pathology by modulating excitability and signaling.

This study investigates sex differences in inflammatory responses and gut microbiota in a progressive monkey model of Parkinson's disease following MPTP treatment.