Daniel J. Lustberg

This study shows that dopamine β-hydroxylase knockout in mice alters innate responses to predator odor, with reduced defensive burying and increased grooming, suggesting NE and DA balance regulates behavioral responses.

This study shows RGS14 protects hippocampal neurons from seizure-induced mitochondrial oxidative stress and pathology by modulating excitability and signaling.

This study uses DSP-4 to model early LC-NE system changes in AD and PD, showing axon damage, neuroinflammation, and behavioral changes without LC cell death.

The paper investigates how norepinephrine and dopamine influence distinct repetitive behaviors in mice exposed to novel odorants, showing differential effects on digging and grooming.

This study investigates how RGS14 affects locomotor behavior and ERK signaling in response to environmental novelty and cocaine in specific limbic regions.

This study investigates the distinct roles of norepinephrine and galanin in stress-induced anxiety-like behavior using genetic and pharmacological approaches in mice.

The paper identifies genetic variants in RGS14 that disrupt nuclear shuttling and impair LTP regulation in hippocampal neurons, with variant LR causing nuclear accumulation and loss of function.

This study investigates the role of central norepinephrine in novelty-induced behaviors, finding that NE signaling is essential for both neophilic and neophobic responses.

The paper investigates the role of norepinephrine in stress-induced repetitive behaviors in OCD models, finding that NE deficiency reduces compulsive behaviors and that restoring NE rescues these behaviors.

This study shows that eliminating galanin in noradrenergic neurons reduces galanin in specific brain regions and alters coping behaviors without affecting norepinephrine levels.

This study shows RGS14 restricts synaptic plasticity in hippocampal CA2 by limiting postsynaptic calcium signaling and downstream pathways.

This study identifies CaM and CaMKII as novel interacting partners of RGS14 in mouse brain, revealing RGS14 as a CaM effector and CaMKII phosphorylation substrate.

This study investigates the role of CA2 pyramidal neurons in hippocampal oscillations and social behavior using DREADDs in mice, finding bidirectional regulation of low gamma oscillations and impaired social approach with inhibition.