CD4-mediated immunity shapes neutrophil-driven tuberculous pathology
Benjamin Henry Gern, Josepha M. Klas, Kimberly A. Foster, Molly E. Kanagy, Sara B. Cohen, Courtney Ray Plumlee, Fergal J. Duffy, Maxwell Lewis Neal, Mehnaz Halima, Andrew T. Gustin, Sylvia M. Stull, Jasmine J. Wilson, Alan H. Diercks, Alan A. Aderem, Michael Gale, , Kevin B. Urdahl
This study shows that prior immunity influences tuberculosis lesion structure by modulating neutrophil and T cell responses, leading to different pathological outcomes.
The Journal of Experimental Medicine · Jun 28, 2025Peer-reviewedImmunology