Author

Lu Bai

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-8779-336XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lu Bai3 papers · Chinese Academy of Sciences

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Chen WangiD· 1 shared Cheng XuiD· 1 shared Erik M. LeithiD· 1 shared Guy M. GeniniD· 1 shared Holly Kleinschmidt· 1 shared Jenna K. Johnson· 1 shared Jia’nan Zeng· 1 shared Jianyu YangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

Chen WangORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Chemo-mechanotherapy of fibrosis: dynamic control of biological materials through tissue-architecture-dependent crosslink disruption

Wenyu Kong, Meiyue Song, Xiangjun Peng, Lu Bai, Jia’nan Zeng, Kaini Liang, Yuhong Jin, Jiaxin Wang, Xue Wang, Yuxuan Huang, Yudi Niu, Lyu Zhou, Xi‐Qiao Feng, Chen Wang, Guy M. Genin, , Yanan Du

This study shows that mechanical stretching can disrupt pathological crosslinks in fibrotic tissues, reversing fibrosis in mice when combined with pharmacological treatment.

bioRxiv · Sep 1, 2025 · PreprintBioengineering

Systematic Dissection of Sequence Features Affecting the Binding Specificity of a Pioneer Factor Reveals Binding Synergy Between FOXA1 and AP-1

Cheng Xu, Holly Kleinschmidt, Jianyu Yang, Erik M. Leith, Jenna K. Johnson, Song Tan, Shaun Mahony, Lu Bai

The paper uses ChIP-ISO to analyze sequence features affecting FOXA1 binding and finds that AP-1 influences FOXA1 binding specificity and context-dependent binding.

Molecular Cell · Jul 16, 2024Peer-reviewedGenetics