Yuxuan Huang

The paper shows synaptopodin enables cells to adapt their adhesion structures to resist perpendicular forces by reorganizing the actin cytoskeleton and integrin-based adhesions.

The paper identifies a mechanical homeostasis mechanism in podocytes where balance between fluid shear stress and cellular contractility prevents injury, showing that reducing blood pressure can worsen outcomes when contractility is impaired.

The paper models how critical cell spacing drives a phase transition in matrix-mediated tissue condensation through mechanical feedback.

This study shows that mechanical stretching can disrupt pathological crosslinks in fibrotic tissues, reversing fibrosis in mice when combined with pharmacological treatment.

This study identifies mechanisms to improve mechanical stiffness in cellulose nanocrystal-reinforced soy protein isolate composites through surface modification and interfacial interactions.