Guosong Hong

This study identifies arginine as a key amino acid for achieving optical transparency in tissues through its ultraviolet absorption and refractive index modulation properties.

The paper develops red-shifted near-infrared fluorescent proteins for deep-tissue SWIR imaging, showing improved signal and imaging depth in vivo.

This paper shows that tartrazine clears live cells effectively at high refractive indices and osmolality without harming cell viability.

This paper introduces a color-neutral and reversible tissue transparency method that enables longitudinal deep-tissue imaging in live mice with high spatiotemporal resolution.

This study records brain activity in awake toads over multiple days using flexible mesh electronics, enabling long-term electrophysiology in non-paralyzed amphibians.

The paper presents a method for fabricating 3D microelectrode arrays to interface with neural structures, demonstrating high-resolution recording from retinal ganglion cells.

This paper introduces an implant-free, tether-free optical neuromodulation technique using NIR-II light to stimulate deep brain regions in mice through the scalp.

The paper identifies neuroprotective genes in retinal ganglion cells by analyzing their resilience to injury using single-cell RNA-seq and functional assays.