Author

Jean-François Rivest

Centre hospitalier universitaire de QuébecORCID 0000-0002-8865-8063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Denis CyriD· 2 shared Paula J. WatersiD· 2 shared Sophie CarteriD· 2 shared Yannick DoyoniD· 2 shared Adeline GouletiD· 1 shared Alexis DuringeriD· 1 shared Claudia Goupil· 1 shared Daniel AgudeloiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Denis CyrORCID

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2 papers

Recent·Most cited

In vivo dissection of the mouse tyrosine catabolic pathway with CRISPR-Cas9 identifies modifier genes affecting hereditary tyrosinemia type 1

Jean-François Rivest, Sophie Carter, Claudia Goupil, Denis Cyr, Roth‐Visal Ung, Dorothée Bouron Dal Soglio, Fabrice Mac‐Way, Paula J. Waters, Massimiliano Paganelli, Yannick Doyon

The paper uses CRISPR-Cas9 in mice to identify modifier genes that affect the severity of tyrosinemia type 1 by editing enzymes in the tyrosine catabolic pathway.

bioRxiv · Sep 29, 2023 · PreprintGenetics

Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9

Daniel Agudelo, Sophie Carter, Minja Velimirovic, Alexis Duringer, Jean-François Rivest, Sébastien Levesque, Jérémy Loehr, Mathilde Mouchiroud, Denis Cyr, Paula J. Waters, Mathieu Laplante, Sylvain Moineau, Adeline Goulet, Yannick Doyon

This paper engineers CRISPR-Cas9 variants from Streptococcus thermophilus to target diverse A-rich PAMs, enabling efficient genome editing in mice.

bioRxiv · Jul 31, 2019Molecular Biology