Author

Nicole Groß

Johns Hopkins UniversityORCID 0000-0002-8936-207XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Elana Judith FertigiD· 2 shared Elizabeth M. JaffeeiD· 2 shared Emma KartaliaiD· 2 shared Jacob T. MitchelliD· 2 shared James M. LeathermaniD· 2 shared Luciane Tsukamoto KagoharaiD· 2 shared Won Jin HoiD· 2 shared Alexei HernandeziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Elana Judith FertigORCID

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2 papers

Recent·Most cited

Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially control regulatory T cell phenotype and function via CXCL9 and CCL22

Saumya Y. Maru, Meredith Wetzel, Jacob T. Mitchell, Nicole Groß, Lalitya Andaloori, Kathryn L. Howe, Emma Kartalia, Guanglan Mo, James Leatherman, Won Jin Ho, Elana Judith Fertig, Luciane Tsukamoto Kagohara, Edward J. Pearce, Elizabeth M. Jaffee

This study shows antigen-presenting cancer-associated fibroblasts (apCAFs) in murine pancreatic tumors influence regulatory T cell phenotype and function through CXCL9 and CCL22, affecting immune checkpoint blockade response.

The Journal of Immunology · Jun 1, 2026Peer-reviewedCancer Biology

Cancer associated fibroblasts drive epithelial to mesenchymal transition and classical to basal change in pancreatic ductal adenocarcinoma cells with loss of IL-8 expression

Samantha R. Guinn, Brayan Perez, Joseph A. Tandurella, Mili Ramani, Jae Woo Lee, Daniel J. Zabransky, Emma Kartalia, Jignasha G. Patel, Haley Zlomke, Norman G. Nicolson, Sarah M. Shin, Benjamin Barrett, Nicholas Sun, Alexei Hernandez, Erin M. Coyne, , Jacquelyn W. Zimmerman

The paper investigates how cancer-associated fibroblasts (CAF) influence tumor cell behavior in pancreatic ductal adenocarcinoma by driving EMT and altering cell subtypes, with IL-8 playing a key modulatory role.

bioRxiv · Jan 7, 2025 · PreprintCancer Biology