Author

Matthew J. Feinstein

Northwestern UniversityORCID 0000-0002-8958-7666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Avishai ShemeshiD· 1 shared Bernat Bramon MoraiD· 1 shared Chunlei CheniD· 1 shared Cloé BrennaiD· 1 shared Constantinos PetrovasiD· 1 shared Daniel G. CheniD· 1 shared Daniel R. CalabreseiD· 1 shared Davi M. Lyra‐LeiteiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

Avishai ShemeshORCID

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Author profile →

3 papers

Recent·Most cited

Follicular Bcl6 reactivity is associated with a unique immune landscape and spatial transcriptome in COVID-19

Cloé Brenna, Bernat Bramon Mora, Kalliopi Ioannidou, Julien Bodelet, Mia Siebmanns, Simon Burgermeister, Spiros Georgakis, Michail Orfanakis, Yannick D. Müller, Nazanin Sédille, Matthew J. Feinstein, Jon W. Lomasney, Oliver Y. Chén, Giuseppe Pantaleo, Sabina Berezowska, , Constantinos Petrovas

The paper analyzes lung-draining lymph nodes from COVID-19 autopsies to identify distinct follicular Bcl6 reactivity subgroups and their associated immune and spatial transcriptomic profiles.

JCI Insight · Sep 9, 2025Peer-reviewedImmunology

CITE-seq analysis reveals human cytomegalovirus and diabetes-associated adaptive NK cell alterations in cardiovascular disease.

Sujit Silas Armstrong Suthahar, Daniel G. Chen, Sunil Kumar, James R. Heath, Matthew J. Feinstein, John R. Greenland, Daniel R. Calabrese, Lewis L. Lanier, Klaus F. Ley, Avishai Shemesh

The paper uses CITE-seq to analyze NK cell alterations in CAD patients, finding SPON2/IFNG ratio and adaptive NK cell signatures correlate with disease severity and inflammation.

International Journal of Molecular Sciences · Feb 6, 2025Peer-reviewedImmunology

Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced diastolic dysfunction

Yuki Tatekoshi, Chunlei Chen, Jason Solomon Shapiro, Hsiang‐Chun Chang, Malorie Blancard, Davi M. Lyra‐Leite, Paul W. Burridge, Matthew J. Feinstein, Richard T. D’Aquila, Priscilla Y. Hsue, Hossein Ardehali

This study uses hiPSC-CMs to model inflammation-induced diastolic dysfunction in HIV patients and tests drug effects on calcium transient.

eLife · Mar 28, 2024Peer-reviewedMolecular Biology