Françoise Ochsenbein

Optimized quantitative bacterial two-hybrid (qB2H) for protein-protein interaction assessment

This paper introduces qB2H, an optimized bacterial two-hybrid system for quantitative PPI analysis, demonstrating improved accuracy and utility in interface mapping and binder optimization.

Rad52 Acts as an Assembly Chaperone to Form and Stabilize Rad51 Filaments Through a Large C-Terminus 85-Residue Segment

This study identifies an 85-residue segment of Rad52 that facilitates Rad51 filament formation and stability through structural and functional analyses in yeast.

BRG1 generates subnucleosomes that expand OCT4 binding and function beyond DNA motifs at enhancers

This study shows BRG1 creates subnucleosomes that allow OCT4 to bind and function at enhancers beyond its DNA motifs.

Histone deposition plays an active role in recombination-dependent replication to balance genome2 stability upon replication stress

The paper shows that histone deposition is essential for completing recombination-dependent replication (RDR) and balancing genome stability during replication stress in fission yeast.