This study shows that ivermectin inhibits extracellular vesicle secretion from parasitic nematodes, suggesting a potential mechanism for its therapeutic effect against lymphatic filariasis.

Journal of Extracellular Vesicles · Dec 1, 2020Peer-reviewedMolecular Biology

Identification of Bovine Genotypes Conferring Diminished Susceptibility to Salmonellosis and Colonization by Salmonella and E. coli O157:H7

Kristi L. Anderson, Duane K. Ramsey, Tim A. Day, Steve A. Carlson

This study identifies a bovine genotype, SYNJ1/SNYJ1::mcr1/mcr1, associated with reduced susceptibility to Salmonella and E. coli O157:H7 in cattle.

bioRxiv · Jul 6, 2020 · PreprintGenetics

Comparative genomics of the major parasitic worms

Avril Coghlan, James Anthony Cotton, Nancy E. Holroyd, Adam James Reid, Diogo M. Ribeiro, Eleanor Stanley, Helen L. Beasley, Hayley M. Bennett, Stephen R. Doyle, Daria Gordon, Bhavana Harsha, Thomas Huckvale, Jane Lomax, Gabriel Rinaldi, Myriam Shafie, , Lian-Chen Wang

This paper compares genomes of 81 nematode and platyhelminth species to identify gene families related to parasitism and prioritize new drug targets.

Nature Genetics · Oct 29, 2018Peer-reviewedGenomics