Author

Colleen J. Mulvihill

The University of Texas at AustinORCID 0000-0002-9049-3405Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andrew D. EllingtoniD· 2 shared Edward M. MarcotteiD· 2 shared Elizabeth C. GardneriD· 2 shared Jimmy GollihariD· 2 shared Björn D. M. BeaniD· 1 shared Brendan M. FloydiD· 1 shared Daniel R. BoutziD· 1 shared Josh Lutgens· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersSynthetic Biology

Andrew D. EllingtonORCID

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2 papers

Recent·Most cited

Humanized CB1R and CB2R yeast biosensors enable facile screening of cannabinoid compounds

Colleen J. Mulvihill, Josh Lutgens, Jimmy Gollihar, Petra Bachanová, Edward M. Marcotte, Andrew D. Ellington, Elizabeth C. Gardner

The paper develops yeast biosensors for CB1R and CB2R to screen cannabinoids and identify structure-activity relationships.

bioRxiv · Oct 12, 2022 · PreprintSynthetic Biology

Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols

Björn D. M. Bean, Colleen J. Mulvihill, Riddhiman K. Garge, Daniel R. Boutz, Olivier Rousseau, Brendan M. Floyd, William Cheney, Elizabeth C. Gardner, Andrew D. Ellington, Edward M. Marcotte, Jimmy Gollihar, Malcolm S. Whiteway, Vincent J. J. Martin

This study engineers yeast to produce cholesterol, enabling functional expression of human opioid and other GPCRs, creating biosensors with measurable agonist responses and antagonist inhibition.

Nature Communications · May 24, 2022Peer-reviewedSynthetic Biology