Author

Shilpa Hebbar

Kansas State UniversityORCID 0000-0002-9078-5731Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anna ZinovyevaiD· 3 shared Ana Karina MoraoiD· 1 shared Christopher M. HammelliD· 1 shared David Q. MatusiD· 1 shared Eric G. MossiD· 1 shared Frances E. Q. MooreiD· 1 shared Ganesh Prabhakar PanzadeiD· 1 shared Jeffrey C. MedleyiD· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Anna ZinovyevaORCID

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3 papers

Recent·Most cited

hnRNPA1/2 homolog hrpa-1 coordinates with miRNAs to regulate gene expression during C. elegans development.

Shilpa Hebbar, Ganesh Prabhakar Panzade, Anna Zinovyeva

The paper shows HRPA-1 interacts with miRNAs and miRISC components in C. elegans, affecting miRNA function and developmental timing.

bioRxiv · Jul 22, 2022 · PreprintMolecular Biology

Single Nucleotide Substitutions Effectively Block Cas9 and Allow for Scarless Genome Editing in Caenorhabditis elegans

Jeffrey C. Medley, Shilpa Hebbar, Joel T. Sydzyik, Anna Zinovyeva

This study shows that single-nucleotide substitutions in the guide sequence block Cas9 activity in C. elegans, enabling efficient genome editing without additional blocking mutations.

Genetics · Nov 15, 2021Peer-reviewedGenetics

An engineered, orthogonal auxin analog/AtTIR1(F79G) pairing improves both specificity and efficacy of the auxin degradation system in Caenorhabditis elegans

Kelly Hills-Muckey, Michael A. Q. Martinez, Natalia Stec, Shilpa Hebbar, Joanne Saldanha, Taylor N. Medwig-Kinney, Frances E. Q. Moore, Maria Ivanova, Ana Karina Morao, Jordan D. Ward, Eric G. Moss, Sevinç Ercan, Anna Zinovyeva, David Q. Matus, Christopher M. Hammell

The paper introduces an engineered auxin analog and AtTIR1(F79G) pair to improve the specificity and efficacy of the auxin degradation system in C. elegans.

Genetics · Oct 12, 2021Peer-reviewedMolecular Biology