Bhama Ramkhelawon

Integrated forward and reverse degradomics uncovers the proteolytic landscape of aortic aneurysms and the roles of MMP9 and mast cell chymase

The paper uses forward and reverse degradomics to analyze proteolytic landscapes in aortic aneurysms, identifying key proteases like MMP9 and CMA1 and their roles in extracellular matrix remodeling.

Pathogenic strains of a gut commensal drive systemic platelet activation and thromboinflammation in lupus nephritis

This study shows that pathogenic Ruminococcus gnavus strains in the gut drive platelet activation and thromboinflammation in lupus nephritis, with antibodies against its lipoglycan as a potential biomarker.

Resolving the design principles that control postnatal vascular growth and scaling

The paper identifies biological principles governing postnatal aortic growth, showing it scales with the vertebral column and relies on differentiated cell proliferation rather than stem cells.