Jonas Braun

Failed Metabolic Adaptation to Stress Underlies Pathogenesis in a Heterozygous Genetic Disorder

This study investigates how stress exacerbates metabolic and oxidative stress in heterozygous Darier disease, leading to disrupted intercellular adhesion and skin lesions.

Resolving the design principles that control postnatal vascular growth and scaling

The paper identifies biological principles governing postnatal aortic growth, showing it scales with the vertebral column and relies on differentiated cell proliferation rather than stem cells.