Melanie Vollmar

Systematic exploration of predicted quaternary structures within pandemic-relevant viral proteomes

The paper predicts quaternary structures of viral proteins using AlphaFold2 and AlphaFold-Multimer, identifying new insights into vaccinology and protease targets.

AlphaFold Database expands to proteome-scale quaternary structures

The paper expands the AlphaFold Protein Structure Database to include proteome-scale quaternary structures, predicting 1.81M high-confidence protein complexes and revealing conserved structural clusters across domains of life.

Structural insights into cobalamin loading and reactivation of human methionine synthase

This study determines the structures of human methionine synthase in apo and cobalamin-bound states, revealing conformational changes and interactions with MMADHC and MTRR that aid in cobalamin loading and activation.

Linking protein residues in literature and structure

The paper introduces a tool that links protein residue mentions in text to their corresponding positions in protein structures, enabling integrated exploration with experimental evidence.

Human-in-the-loop approach to identify functionally important residues of proteins from literature

The paper presents a human-in-the-loop system for identifying residue-level functional annotations from literature, achieving high precision, recall, and F1-measure.