This study identifies the Type IX Secretion System as a key virulence factor in Chryseobacterium nematophagum's ability to kill Caenorhabditis elegans.

bioRxiv · Sep 26, 2026 · PreprintMicrobiology

CGC1, a new reference genome for Caenorhabditis elegans

Kazuki Ichikawa, Massa J. Shoura, Karen L. Artiles, Dae‐Eun Jeong, Chie Owa, Haruka Kobayashi, Yoshihiko Suzuki, Manami Kanamori, Yu Toyoshima, Yuichi Iino, Ann E. Rougvie, Lamia Wahba, Andrew Z. Fire, Erich M. Schwarz, Shinichi Morishita

The paper presents a new gap-free, telomere-to-telomere reference genome for C. elegans, CGC1, improving upon previous assemblies and providing a more complete genome.

Genome Research · Aug 1, 2025Peer-reviewedGenomics

Reduction of insulin/IGF-1 receptor rejuvenates immunity via positive feedback circuit

Yujin Lee, Yoonji Jung, Dae‐Eun Jeong, Wooseon Hwang, Seokjin Ham, Hae‐Eun H. Park, Sujeong Kwon, Jasmine M. Ashraf, Coleen Tara Murphy, Seung‐Jae Lee

This study shows that reducing insulin/IGF-1 receptor activity delays immunosenescence and rejuvenates immunity in C. elegans through a positive feedback circuit involving DAF-16/FOXO and HSF-1.

The Journal of Cell Biology · Feb 11, 2021Peer-reviewedGenetics

Identification of a pangolin niche for a 2019-nCoV-like coronavirus through an extensive meta-metagenomic search

Lamia Wahba, Nimit Jain, Andrew Z. Fire, Massa J. Shoura, Karen L. Artiles, Matthew J. McCoy, Dae‐Eun Jeong

The paper performs a meta-metagenomic search to identify potential environmental niches for 2019-nCoV by analyzing virome datasets from the NCBI Sequence Read Archive.

bioRxiv · Feb 8, 2020 · PreprintBioinformatics