Author

Michelle A. Hsu

Mayo ClinicORCID 0000-0002-3214-2607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Haidong DongiD· 2 shared Adrian T. TingiD· 1 shared Akhilesh PandeyiD· 1 shared Allison R. CarriD· 1 shared Daniel D. BilladeauiD· 1 shared Dusan BogunoviciD· 1 shared Emilia Rae DellaceccaiD· 1 shared Erica N. Krogman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Haidong DongORCID

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2 papers

Recent·Most cited

ImmunologyScience SignalingPeer-reviewedJul 7, 2026

TBK1 and IKKϵ protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanism

Nicholas D. Sun, Allison R. Carr, Erica N. Krogman…·Adrian T. Ting

This study shows that TBK1 and IKKε protect target cells from IFNγ-mediated T cell killing by suppressing inflammatory apoptosis and NFκB-driven inflammation.

2 citations

humanexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 18, 2025

PD-1 prelimits both the cytotoxic and exhaustion potential in thymic CD8+ T cells and impacts the maintenance of peripheral tumor immunity

Zhiming Mao, Jacob B. Hirdler, Joanina K. Gicobi…·Haidong Dong

This study identifies PD-1's role in regulating effector potential and exhaustion in thymic CD8+ T cells, showing that PD-1 inhibition enhances expansion but leads to exhaustion in tumor tissues.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky