María Jesús Ruiz-Rodríguez

This study shows that disrupting TGFβ signaling in adult mice makes the aorta susceptible to hypertension-induced dissection, even from short-term blood pressure increases.

This study identifies the HBP-ISR axis as a driver of thoracic aortic aneurysm in Marfan Syndrome, showing that targeting this pathway can reverse aortic dilation in mice and is associated with human TAAD.