Pengwei Ren

This study shows that C9, a component of membrane attack complexes, forms non-cytolytic intracellular aggregates that promote inflammation and EC activation through aggrephagy and NF-κB activation.

This study shows that disrupting TGFβ signaling in adult mice makes the aorta susceptible to hypertension-induced dissection, even from short-term blood pressure increases.

The paper analyzes single-cell transcriptomes of aortic smooth muscle cells in mice to show distinct origins and similar transcriptional changes after TGFβ signaling disruption.