Author

Thaddeus J. Kunkel

Oregon Health & Science UniversityORCID 0000-0002-9458-6000Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adam M. CoombsiD· 1 shared Andrew P. LiebermaniD· 1 shared Ben EmeryiD· 1 shared David B. LombardiD· 1 shared Elyse M. Petrunak· 1 shared Fathiya M. Al-Murshedi· 1 shared Iris N. FarnumiD· 1 shared Jaap KeijeriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adam M. CoombsORCID

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2 papers

Recent·Most cited

Temporal Requirement for Stearoyl-CoA Desaturase 1 in Oligodendrocyte Development but Not Myelin Maintenance

Iris N. Farnum, Thaddeus J. Kunkel, Adam M. Coombs, Ben Emery, Manideep Chavali

This study shows that Scd1 is required for oligodendrocyte development and myelination but not for maintaining mature myelin.

Journal of Neuroscience · Apr 7, 2026Peer-reviewedNeuroscience

SIRT5 variants from patients with mitochondrial disease are associated with reduced SIRT5 stability and activity, but not with neuropathology

Taolin Yuan, Surinder Kumar, Mary E. Skinner, Ryan Victor-Joseph, Majd Abuaita, Jaap Keijer, Jessica Zhang, Thaddeus J. Kunkel, Yanghan Liu, Elyse M. Petrunak, Thomas L. Saunders, Andrew P. Lieberman, Jeanne A. Stuckey, Nouri Neamati, Fathiya M. Al-Murshedi, , David B. Lombard

The paper identifies two SIRT5 variants in mitochondrial disease patients that reduce protein stability and activity but not neuropathology, using biochemical and mouse model analyses.

bioRxiv · Dec 6, 2023 · PreprintGenetics