Author

Mary E. Skinner

University of MichiganORCID 0000-0002-3853-1478Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Adam KlaissiD· 1 shared Andrew P. LiebermaniD· 1 shared Asa W. Huffaker· 1 shared Ashley Scheutzow· 1 shared David B. LombardiD· 1 shared Elyse M. Petrunak· 1 shared Fathiya M. Al-Murshedi· 1 shared Jaap KeijeriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Adam KlaissORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedFeb 4, 2026

HSP-1-Specific Nanobodies Alter Chaperone Function in vitro and in vivo

Nicholas D. Urban, Kunal Gharat, Zachary Mattiola…·Matthias C. Truttmann

This study develops two nanobodies that specifically target HSP-1, reducing its ATPase activity and protein folding capacity both in vitro and in vivo.

DOI 10.1016/j.jbc.2026.111238

C. elegansproteomics

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GeneticsbioRxivPreprintDec 6, 2023

SIRT5 variants from patients with mitochondrial disease are associated with reduced SIRT5 stability and activity, but not with neuropathology

Taolin Yuan, Surinder Kumar, Mary E. Skinner…·David B. Lombard

The paper identifies two SIRT5 variants in mitochondrial disease patients that reduce protein stability and activity but not neuropathology, using biochemical and mouse model analyses.

DOI 10.1101/2023.12.06.570371

humanexperimental assay

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