Author

Victoria Auerbuch

University of California, Santa CruzORCID 0000-0002-9475-4756Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Diana Fernandez Pacheco· 2 shared Caia Lomeli· 1 shared Cammie F. LesseriD· 1 shared Christine JacobsiD· 1 shared Derfel TercianoiD· 1 shared Diana Hooker-RomeroiD· 1 shared Erin L. MettertiD· 1 shared George Imre BalazsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Diana Fernandez Pacheco

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2 papers

Recent·Most cited

IscR-mediated sensing of iron-sulfur cluster demand coordinates virulence gene expression in Yersinia pseudotuberculosis

Mané Ohanyan, George Imre Balazs, Karthik Hullahalli, Diana Fernandez Pacheco, Caia Lomeli, Katherine G. Dailey, Erin L. Mettert, Diana Hooker-Romero, Leah Schwiesow, Patricia J. Kiley, Matthew K. Waldor, Victoria Auerbuch

This paper shows that IscR, an iron-sulfur cluster sensor, regulates virulence gene expression in Yersinia pseudotuberculosis by responding to iron and oxygen levels, with mutations altering infection dynamics.

bioRxiv · Oct 16, 2025 · PreprintMicrobiology

The polyadenylase PAPI is required for virulence plasmid maintenance in pathogenic bacteria

Katherine Schubert, Jessica Zhang, Michele E. Muscolo, Micah Braly, Joshua W. McCausland, Hanh N. Lam, Karen Hug, Matthew Loven, Santiago Ruiz Solis, Melissa Estrada Escobar, Henry Moore, Derfel Terciano, Diana Fernandez Pacheco, Todd M. Lowe, Cammie F. Lesser, , Victoria Auerbuch

This study identifies PAPI (encoded by pcnB) as essential for maintaining virulence and AMR plasmid copy number, stability, and bacterial virulence in Yersinia and Shigella.

PLoS Pathogens · May 27, 2025Peer-reviewedMicrobiology